Einstein International Journal Organization(EIJO)

Recent advances in nanoscience and nanotechnology have radically revolutionized how we diagnose, treat, and prevent disease in all aspects of human life. Among the numerous metallic nanoparticles employed in biomedical applications, silver nanoparticles (AgNPs) are among the most important and intriguing nonmaterials. AgNPs have considerable applications in nanoscience and nanotechnology, particularly in nanomedicine. Although other noble metals have been used for a number of reasons, AgNPs have garnered attention due to their potential applications in cancer detection and antibacterial capabilities. The AgNPs were characterized by UV-Vis Spectroscopy, Scanning Electron Microscopy (SEM), Energy-Dispersive X-Ray Spectroscopy (EDX), Fourier-Transform Infrared Spectroscopy (FTIR), and Dynamic Light Scattering (DLS). Nanoparticles can be produced via physical, chemical, or biological means. In this review, we look at the physical, chemical, and biological techniques of producing AgNPs. The biological synthesis of nanoparticles, also known as green synthesis is an environmentally friendly and cost-effective procedure. We also evaluate the elements that influence AgNP generation and the ways for defining them. More importantly, we discuss the multifunctional bio-applications of AgNPs, including antibacterial, antifungal, antiviral, anti-angiogenic, and anti-cancer agents, as well as the mechanism of AgNP anti-cancer activity. Finally, we will discuss the future prospects for AgNPs.

Keywords: green synthesis, silivernano particles, characterization, plant extract, anticancer and antidiabetics

1. Abou El-Nour, K.M., Eftaiha, A.A., Al-Warthan, A. and Ammar, R.A., 2010.Synthesis and applications of silver nanoparticles. Arabian journal of chemistry, 3(3), pp.135-140.
2. Ahmad, S., Munir, S., Zeb, N., Ullah, A., Khan, B., Ali, J., Bilal, M., Omer, M., Alamzeb, M., Salman, S.M. and Ali, S., 2019. Green nanotechnology: A review on green synthesis of silver nanoparticles—An ecofriendly approach. International journal of nanomedicine, pp.5087-5107..
3. Ali, T., Warsi, M.F., Zulfiqar, S., Sami, A., Ullah, S., Rasheed, A., Alsafari, I.A., Agboola, P.O., Shakir, I. and Baig, M.M., 2022. Green nickel/nickel oxide nanoparticles for prospective antibacterial and environmental remediation applications. Ceramics International, 48(6), pp.8331-8340.
4. Alvarez, R.A., Cortez-Valadez, M., Bueno, L.O.N., Hurtado, R.B., Rocha-Rocha, O., Delgado-Beleño, Y., Martinez-Nuñez, C.E., Serrano-Corrales, L.I., Arizpe-Chávez, H. and Flores-Acosta, M., 2016.Vibrational properties of gold nanoparticles obtained by green synthesis. Physica E: Low-dimensional Systems and Nanostructures, 84, pp.191-195.
5. Baba, S.A. and Malik, S.A., 2014. Evaluation of antioxidant and antibacterial activity of methanolic extracts of Gentianakurrooroyle. Saudi Journal of Biological Sciences, 21(5), pp.493-498.
6. Banerjee, P., Satapathy, M., Mukhopahayay, A. and Das, P., 2014. Leaf extract mediated green synthesis of silver nanoparticles from widely available Indian plants: synthesis, characterization, antimicrobial property and toxicity analysis. Bioresources and Bioprocessing, 1, pp.1-10.
7. Banerjee, P., Satapathy, M., Mukhopahayay, A. and Das, P., 2014. Leaf extract mediated green synthesis of silver nanoparticles from widely available Indian plants: synthesis, characterization, antimicrobial property and toxicity analysis. Bioresources and Bioprocessing, 1, pp.1-10.
8. Bekele, E.T., Gonfa, B.A., Zelekew, O.A., Belay, H.H. and Sabir, F.K., 2020. Synthesis of titanium oxide nanoparticles using root extract of Kniphofiafoliosa as a template, characterization, and its application on drug resistance bacteria. Journal of Nanomaterials, 2020, pp.1-10.
9. Chandran, S.P., Chaudhary, M., Pasricha, R., Ahmad, A. and Sastry, M., 2006.Synthesis of gold nanotriangles and silver nanoparticles using Aloevera plant extract. Biotechnology progress, 22(2), pp.577-583.
10. Chouhan, R.S., Horvat, M., Ahmed, J., Alhokbany, N., Alshehri, S.M. and Gandhi, S., 2021. Magnetic nanoparticles—A multifunctional potential agent for diagnosis and therapy. Cancers, 13(9), p.2213.