Article Overview
Abstract
The pharmaceutical sector is always changing as a result of improvements in data analysis and artificial intelligence (AI), which are driving advances in medication research and development. This article examines how artificial intelligence (AI) is revolutionizing the pharmaceutical industry, emphasizing how AI may improve medication discovery, streamline development procedures, and improve monitoring tactics. Moreover, real-time medication effectiveness and safety monitoring is made easier by AI-powered data analysis. Facilitating proactive modifications and tailored therapeutic strategies. While tackling issues like exorbitant prices and protracted research times, the use of AI into pharmaceutical innovation has the potential to expedite the delivery of innovative treatments. An extensive summary of these developments is given in this article, which also shows how artificial intelligence (AI) is influencing pharmaceutical innovation going forward and facilitating more productive and successful drug research and development procedures.
Keywords: Medication Discovery, Drug Research and Development, Innovation in Pharmacies, Human-machine intelligence (AI), Robotic Learning, Data Analysis for Deep Learning, Clinical Investigations.
Reference
- Mak, K. K., Wong, Y. H., & Pichika, M. R. (2023). Artificial intelligence in drug discovery and development. Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays, 1-38.
- Kolluri, S., Lin, J., Liu, R., Zhang, Y., & Zhang, W. (2022). Machine learning and artificial intelligence in pharmaceutical research and development: a review. The AAPS journal, 24, 1-10.
- Narayanan, R. R., Durga, N., & Nagalakshmi, S. (2022). Impact of artificial intelligence (AI) on drug discovery and product development. Indian Journal of Pharmaceutical Education and Research, 56(3), S387-S397.
- Sahu, A., Mishra, J., & Kushwaha, N. (2022). Artificial intelligence (AI) in drugs and pharmaceuticals. Combinatorial chemistry & high throughput screening, 25(11), 1818-1837.
- Terranova, N., Renard, D., Shahin, M. H., Menon, S., Cao, Y., Hop, C. E., ... & Lu, J. (2024). Artificial intelligence for quantitative modeling in drug discovery and development: An innovation and quality consortium perspective on use cases and best practices. Clinical Pharmacology & Therapeutics, 115(4), 658-672.
- Sampene, A. K., & Nyirenda, F. (2024). Evaluating the effect of artificial intelligence on pharmaceutical product and drug discovery in China. Future Journal of Pharmaceutical Sciences, 10(1), 58.
- Choi, M. S., Kim, M. J., & Kim, K. J. (2019). Curcumin-loaded nanoparticles: A novel approach to the treatment of chronic diseases. Nanomedicine, 14(11), 1571-1586. https://doi.org/10.2217/nnm-2019-0146
- Dubey, P., & Singh, N. (2021). Nanocapsules for curcumin delivery: Current status and future directions. Biotechnology Advances, 50, 107-123. https://doi.org/10.1016/j.biotechadv.2021.107659
- Anand, P., Kunnumakkara, A. B., Newman, R. A., & Aggarwal, B. B. (2007). Curcumin and cancer: An “old-age” disease with an “age-old” solution. Cancer Letters, 255(2), 155-165. https://doi.org/10.1016/j.canlet.2007.01.029
- Bhawna, B., & Kaur, M. (2019). A review on curcumin and its novel formulation. Journal of Drug Delivery and Therapeutics, 9(2), 232-240. https://doi.org/10.22270/jddt.v9i2.2486
- Sarkar, C., Das, B., Rawat, V. S., Wahlang, J. B., Nongpiur, A., Tiewsoh, I., ... & Sony, H. T. (2023). Artificial intelligence and machine learning technology driven modern drug discovery and development. International Journal of Molecular Sciences, 24(3), 2026.
- Choi, M. S., Kim, M. J., & Kim, K. J. (2019). Curcumin-loaded nanoparticles: A novel approach to the treatment of chronic diseases. Nanomedicine, 14(11), 1571-1586. https://doi.org/10.2217/nnm-2019-0146
- Cui, Y., & Li, M. (2021). Cyclodextrin-based drug delivery systems: A review of their applications in cancer therapy. Journal of Pharmaceutical Sciences, 110(1), 12-20. https://doi.org/10.1016/j.xphs.2020.08.035
- Dash, A. K., & Poonam, G. (2021). Self-emulsifying drug delivery systems for enhanced oral bioavailability of curcumin: A review. Journal of Drug Delivery Science and Technology, 62, 102202. https://doi.org/10.1016/j.jddst.2021.102202
- Debnath, N., & Choudhury, H. (2018). Advances in nanoparticle-based delivery systems for curcumin: A review. Drug Development and Industrial Pharmacy, 44(10), 1610-1623. https://doi.org/10.1080/03639045.2018.1471188
- Dery, M., & Gautam, M. (2020). Solid lipid nanoparticles: A versatile delivery system for curcumin. Journal of Controlled Release, 319, 210-223. https://doi.org/10.1016/j.jconrel.2020.02.045
- Dubey, P., & Singh, N. (2021). Nanocapsules for curcumin delivery: Current status and future directions. Biotechnology Advances, 50, 107-123. https://doi.org/10.1016/j.biotechadv.2021.107659
- Eweas, A. F., & Rania, M. (2019). Novel liposomal formulations for curcumin delivery: Efficacy and safety in preclinical models. International Journal of Nanomedicine, 14, 3509-3522. https://doi.org/10.2147/IJN.S194631
- Colombo, S. (2020). Applications of artificial intelligence in drug delivery and pharmaceutical development. In Artificial intelligence in healthcare (pp. 85-116). Academic Press.
- Gupta, S. C., & Sung, B. (2013). Cancer drug discovery and development: Curcumin as a potential candidate. Pharmacological Research, 67(1), 48-57. https://doi.org/10.1016/j.phrs.2012.09.014
- Gutiérrez, M., & Rodríguez-Gascón, A. (2018). Formulation and evaluation of curcumin nanoparticles: A review. Journal of Nanoparticle Research, 20(1), 10. https://doi.org/10.1007/s11051-017-4023-4
- Han, X., & Zhang, Y. (2021). Advances in nanocarrier-based drug delivery systems for curcumin: A review. Journal of Nanoscience and Nanotechnology, 21(9), 5336-5350. https://doi.org/10.1166/jnn.2021.18942
- Husnain, A., Rasool, S., Saeed, A., & Hussain, H. K. (2023). Revolutionizing pharmaceutical research: harnessing machine learning for a paradigm shift in drug discovery. International Journal of Multidisciplinary Sciences and Arts, 2(2), 149-157.
- Jiang, X., & Li, L. (2020). Liposomal and nanoparticle-based delivery systems for curcumin: Current developments and future perspectives. Pharmaceutics, 12(12), 1134. https://doi.org/10.3390/pharmaceutics12121134